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Testicle Cancer


Testicle cancer/testicle carcinoma is a malignant tissue proliferation that is developed by the men’s germ cells (parent cells of the sperms). The characterization “testicle cancer”, “malignant testicle cancer” and “germ cell cancer” mean all exactly the same form of cancer. Malignant is the testicle cancer because it destroys the healthy testicle tissue very fast and can spread to all organs very quickly. Without a medical treatment the tumour is lethal – 30 years ago almost all patients suffer from this cancer form died. Today the testicle cancer can be healed when it is diagnosed and treated at an early stage of the disease. Above all men at the age of 20 to 40 suffer from testicle cancer. It is within this age group the most common cancer disease.
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In Germany every year approximately 4100 young men fall sick with testicular cancer. The genesis of the tumour growth has not been yet identified. Already during the development of a child in the womb false programmed germ cells can be emerged in the testicles of the unborn child; out of these cells the testicle cancer is developing later. After the baby was born the false programmed germ cells are in a sleeping modus. The hormone production during the pubescence can activate these sleeping cells (TIN cells) so that they can produce the malignant cancer cells. The existence of TIN cells can be diagnosed years before the testicle cancer is diagnosed by means of microscopic testing.

A increased risk of suffering from testicle cancer exists for male persons

• With congenital retained testis
• A family disposition

Worldwide the number of people suffering from testicle cancer has increased considerably; the reason for this increase has not yet been found out.

Depending on the tissue characterization of the tumour, testicle cancer is divided into different groups: seminomal carcinoma, teratoid tumours, and mixed cell tumours. The differentiation is important as the medical treatment depends on the kind of tissue differentiation.
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Most men do not recognize the first symptoms of the testicle cancer by themselves. Typical symptoms are:

  • A swelling or a knot in the testicles – mostly pain free
  • Back pain by enlarged lymph nodes in the back of the abdomen
  • An enlarged are hurting mammary gland

Men who recognize alterations to the testicles should consulate a doctor as soon as possible. Experienced in diagnostic and medical treatment is always an urologist.

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If there is a suspicion of testicle cancer the doctor will feel the testicle cautiously. Afterwards an ultrasound examination is made to diagnose more closely than the doctor’s hands can. The blood is screened on proteins that the tumour is producing and can therefore be found to an increased level in the patient’s blood (tumour marker). With these simple and pain-free examinations is in most of the cases possible to diagnose the tumour adequately. The last securing examination is the uncovering of the diseased testicle and the taking of tissue samples by means of an incision in the area of the groin. If the suspicion is confirmed by a microscopic testing, the testicle needs to be removed within the same surgical procedure. The healthy testicle of the opposite side is taking over the function which means that no long-term side effects occur.

After the operation more examinations must be made to find out if the tumour has already spread in the body of the patient. This examination is made by a computerized tomography of the lung and the abdominal area. Repeated blood screenings give information on the stadium of the disease: in stadium 1 the tumour is limited to the testicles, in stadium 2 the tumour has spread to the lymph nodes to the back of the abdomen and in stadium 3 there are metastases in the lymph nodes outside the abdomen area or in other organs. weiter zur Therapie...
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In every stadium of the cancer the testicle tumor can be healed. The biggest chances for becoming healthy again medical experts expect from the operation, chemotherapy and radiation therapy.

As often young patients suffer from testicle cancer, before the medical treatment starts the conservation of the patient’s sperm is discussed. Afterwards depending on the stadium of the cancer and the tumor characterization chemotherapy, a radiation therapy or maybe an operation follows, all under constant monitoring of the patient.

The simple monitoring strategy is always possible when the tumor is less aggressive and has not yet spread to another organ. If the tumor is characterized as a seminomal carcinoma, the metastasis in the lymph nodes can be treated with radiation therapy. Mixed tumor forms respectively teratoma carcinoma is treated in this stadium by means of chemotherapy.

Radiation therapy:
The aim of the radiation therapy is to destroy cancer cells. High-energetic radiation damages the cancer cells and blockades their augmentation. The radiation therapy is a regional applied therapy form (in comparison to the chemotherapy); the patient is treated with radiotherapy on 5 days per week for approx. 5 minutes. The duration of the treatment depends on the spreading of the tumor.

Chemotherapy:
Chemotherapy is normally applied when it comes to teratoma, as these cancer cells not respond to radiation therapy. The basis for the chemotherapy is the principle that the cancer cells, that are dividing fast, are destroyed. The cystostatic therapy shall stop the growth of the tumor cells as they are influencing the cleavage of cells. The testicle tumors belong to the fast spreading and growing cancer forms but can be treated successfully with chemotherapy. Chemotherapy is a high effective “cocktail” of active ingredients and different cystostatic medications. These medications are given through an arm vein infusion in 1 to 4 cycles within 5 days. Between two cycles there is a pause if 2 weeks for the patient until the next treatment cycle starts. Side effects like vomiting and loss of hair cannot be totally avoided.
If after the treatments are still tumor cells left, these tumor cells are surgically removed. As soon as the acute phase of the cancer treatment is overcome, the next phase starts: the tumor after-care.

The after care has the following functions:

  • to diagnose the testicle cancer in time in case the cancer is coming back
  • to diagnose concomitant diseases and consecutive symptoms and diseases
  • When it comes to psychic, physical and social problems offering help for the patient and its family. Part of the treatment is the rehabilitation of any impairments due to the disease and the regeneration of the ability to work
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Darum sollten Sie zu uns kommen
Every year in our Clinic Centre for Urology we treat numerous young men suffering from this form of cancer. In Bavaria we are a centre for second opinion financed by the AOK (public health insurance organization) that also advises other colleagues at any time.

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